Neuroblastoma cells

It develops from specialised nerve cells (neuroblasts) left behind from a babyaposs development in the womb. Neuroblastoma - Symptoms and causes - Mayo Clinic Neuroblastoma is a rare type of cancer that mostly affects babies and young children. American Cancer Society Mar 1 20The main cells that make up the nervous system are called nerve cells or neurons. Neuroblastoma (NB) cell lines are transforme neural crest derived cells, capable of unlimited proliferation in vitro. These cell lines retain the ability of differentiation into neuronal cell types on treatment with various agents.

Neuroblastoma - established neuroblastoma cell lines varies (see Biological features) with cells having a neuroblastic, intermediate and substrate-adherant or flat morphology ( 10). The ability for researchers to differentiate SH-SY5Y neuroblastoma cells into cells possessing a more mature, neuron-like phenotype through manipulation of the culture medium has afforded numerous benefits in the field of neuroscience research.

These cells interact with other types of cells in the body by releasing tiny amounts of chemicals (hormones). Advantages include the capacity for large-scale expansion prior to differentiation, with. Cultures may be homogeneous or heterogeneous for these cell types. This is important, because neuroblastoma cells often release certain chemicals that can cause symptoms (see Signs and Symptoms of Neuroblastoma). Reports of the adaptation of neuroblastoma cell lines to serum-free.

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Neuroblastoma cell lines-a versatile in vitro model in

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